Chris Reedy has spent his life on the move — whether by land or through the air. But the lifelong pilot found himself grounded after a cancer diagnosis that threatened to end his flying career.
His ability to fly and run again was restored thanks to a special procedure Mayo Clinic surgeons call "onco-regeneration" — a partnership between orthopedic oncologists and plastic surgeons that returns muscle strength and function to patients who have lost them after surgery to remove soft tissue sarcoma.
Had his condition occurred a few years earlier, Chris may not have made such a remarkable recovery from the severe calf pain that interrupted one of his regular evening jogs just before his 53rd birthday in 2019.
Chris’ wife, Davie, a nurse, insisted he seek medical attention after the swelling of his leg hadn’t subsided in a few days. Local providers initially diagnosed a pulled muscle. But three months later, a concerning lump remained on the back of his knee. An MRI revealed that he had cancer in his thigh.
Davie reached out to a contact she had at Mayo Clinic, Alexander Shin, M.D., an orthopedic hand and microvascular surgeon. It was recommended that Chris make an appointment at Mayo Clinic.

A Rare Diagnosis
Chris flew himself and Davie from their Overland Park, Kansas, home to Rochester, Minnesota, to meet with Mayo Clinic’s Matthew Houdek, M.D., an associate professor of orthopedic surgery and the fellowship director for musculoskeletal oncology.
Chris had myxoid liposarcoma, an extremely rare form of cancer. Although it had been caught before it metastasized, Chris still needed five-day-a-week radiation sessions for five weeks, followed by surgery.
When Chris asked if he should go back home for treatment, Dr. Houdek’s response made the decision clear.
“I could see him thinking about how to nicely say it,” Chris recalls. “He said, ‘Well, I’m sure they’re good, but my team sees this type of cancer every day of the week. Most other places don’t see more than one of this type of cancer a year.’”
That was all it took for Chris to know he should stay at Mayo Clinic.



Matthew Houdek, M.D., Steven Moran, M.D., and Peter Rose, M.D.
A Breakthrough Approach
Dr. Houdek and Steven Moran, M.D., a Mayo Clinic plastic surgeon, led the surgical team that operated on Chris in 2019. It quickly became clear there was no saving Chris’ hamstring. Cancer had consumed nearly all of it, and doctors took the rest.
To replace it, they took a latissimus dorsi muscle from Chris’ back and fashioned it into a new hamstring.
“They basically had to play the board game Operation with me,” Chris jokes. “It was amazing.”
The Road to Recovery
It was three months before Chris was allowed to put any weight on his leg. Six months later, he was able to walk up to three miles at a time.
“Mr. Reedy is a testament to how resilient patients with a soft tissue sarcoma are,” Dr. Houdek says. “He did the hard work in the recovery process to get to where he is now.”
By using onco-regeneration, Mayo Clinic surgeons had leveraged the body’s ability to regenerate muscle strength.
“It takes a team to be able to do these procedures,” Dr. Houdek says. “Thankfully we have the collaboration between us, our plastic surgeons, radiation oncologists and medical oncologists to advance functional outcomes for patients undergoing limb salvage surgery.”
Taking Flight Again
Two years after the surgery, Chris was back to jogging. But his real goal was to return to the cockpit.
Chris learned how to fly while in college and is the president and CEO of Butler National Corporation, an aerospace and professional services company. He worried he might not ever pilot a plane again.
“Flying is awesome,” says Chris, who shares two planes with his brother and uncle. “It devastated me to think about not being able to fly again. But Dr. Houdek was always so positive about regenerative medicine. He has outcomes that other people don’t.”

Cleared for Takeoff
Chris’ friends in the aviation community told him that if he could get a recommendation from Mayo Clinic, it would help him in his quest to get his pilot’s medical certificate back. Almost a year to the day from his surgery, with the help of Steven Robinson, M.B.B.S., he received a letter of recommendation from Mayo Clinic’s Section of Aerospace Medicine. Shortly thereafter, the Federal Aviation Administration provided a special medical authorization restoring his pilot privileges.
A 2022 recurrence of cancer also didn’t slow Chris down when a tumor was found on his spine. He sent his MRI results to Dr. Houdek, and a few days later Chris was in Rochester, being introduced to Peter Rose, M.D., an orthopedic surgeon at Mayo Clinic.
Dr. Rose removed the tumor from Chris’ back without hampering his mobility so that Chris could get back to what he loves — living life without limits.
“Within about a month, I was back in action,” Chris says. “Mayo Clinic doctors are phenomenal. They’re skilled and exceptionally intelligent, and they get back to you much quicker than other doctors do when you send them a message. They just take great care of you.”
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