Mayo Clinic Platform is leading an unprecedented effort to safely collect and curate the world’s healthcare data. Built on a collection of 54 million patient records — the largest portfolio of high-quality, de-identified data in the world — Platform is an empowering ecosystem where developers of high-tech solutions and dedicated clinicians can come together to build tools and resources that enhance patient care and improve healthcare efficiency and accessibility.
Discover three ways Platform is translating vision into action — and data into solutions.
‘Virtual Clinical Trials’ Point to New Treatment Options for Heart Failure
Bringing a new drug therapy to market can cost up to $1 billion and take over a decade. As drug testing and approvals slowly unfold, many patients continue to suffer. But what if there was a way to test the ability of existing drugs to treat challenging conditions?
Using data drawn from Mayo Clinic Platform — specifically, the de-identified records of nearly 60,000 patients with heart failure — Nansu Zong, Ph.D., and his team were able to virtually assess the ability of certain already-approved drugs to treat heart failure. Instead of recruiting participants, the team drew on patient records to form control groups. They then used advanced artificial intelligence (AI) models that predict how drugs interact with biological systems to determine outcomes. This approach allowed researchers to rapidly test over a dozen medications already on the market without requiring the lengthy, difficult process of conducting a full clinical trial for each one.
“We’ve shown that within our framework, we can say with high confidence if a drug is likely to succeed or not,” Dr. Zong says. The results of the study have been published in NPJ Digital Medicine.
Mayo Clinic teams are now working to refine this new virtual approach to drug testing. While real-world clinical trials will always be essential, virtual options could help to expand and supplement their findings.
To learn more, visit Mayo Clinic News Network.
15 Startups Use Platform Data to Shape Solutions
Mayo Clinic Platform regularly accepts promising tech startups into its incubator program, Mayo Clinic Platform_Accelerate. Participants gain access to Platform data — and the insights of Mayo Clinic experts — as they refine their devices, apps, algorithms and other products. The companies below all “graduated” in the April 2025 Accelerate cohort:
- Bloom Standard has developed a device that can be used to provide quick and effective heart and lung ultrasounds for children.
- Ethos uses AI to monitor alcohol use and predict risk of liver disease and other complications.
- OPTT is a digital mental health platform that provides clinicians with validated tools for evaluating and treating patients more effectively.
- Smart Opinion, Inc. uses AI to detect breast cancer earlier, particularly in women with dense breast tissue.
- Splink, Inc. is harnessing the power of AI to deliver earlier diagnoses for brain disorders like dementia, depression and schizophrenia.
- Voythos uses machine learning to help surgeons predict when patients with complex aortic disease may experience complications, allowing for earlier and more effective interventions.
Mayo Clinic Platform_Accelerate aims to speed up the development of innovative healthcare solutions that can improve patient care and transform medicine.
To learn more about these startups and other Accelerate graduates, visit Mayo Clinic News Network.
PlatforMed Conference Generates Patient-Focused Insights
In June 2025, Mayo Clinic hosted more than 250 leaders from healthcare, government, business and academia at the PlatforMed conference in Minneapolis. The goal: To discuss how sharing data and collaborating through platform technologies produces better care for patients. Speaker highlights included:
- John D. Halamka, M.D., M.S., Dwight and Dian Diercks President of Mayo Clinic Platform, who described how platform-based advances will help aging patients consistently access quality care. The automation and accessibility that platform tools deliver will ensure these patients aren’t overlooked in a future where healthcare resources may be more limited.
- Maneesh Goyal, chief operating officer of Mayo Clinic Platform, who discussed how Mayo Clinic Platform is enabling an average of 60 patients a day to receive hospital-quality care at home through the Advanced Care at Home program. He likened this Platform-powered development to a new “virtual floor” connected to existing Mayo Clinic hospitals.
- Patrick Woodard, M.D., M.H.A., of Monument Health, who explained how platform technologies are helping democratize access to care. As chief information officer of a hospital in rural South Dakota, he can use shared data and tools to ensure his patients have access to the same standard of care as patients in major urban centers.
- Deepak Abraham, Ph.D., M.B.A., of King Hamad American Mission Hospital in Bahrain, who discussed how platform technologies are helping providers save time on tasks like data entry, allowing them to spend more time interacting directly with patients. “The doctor-patient relationship is sacrosanct,” he emphasized. “Platform enhances that.”
To hear more from these and other speakers, watch the episode of Tomorrow’s Cure below, which was recorded at the conference.
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“Mayo brought in experts to show us how to build this product in a best-in-class way that’s safe for patients."
“In five years’ time, I want to be talking about the number of patient lives we’ve saved."
“Without Accelerate, I don’t think our company would have gotten to where we are today."
