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Luminare

Using AI to predict which patients are most at risk of developing sepsis and intervening sooner

By Kathleen Hull Photography by Paul Flessland

Luminare sparked excitement among the Accelerate team because it was taking an approach to sepsis — the No. 1 cause of patient death in hospitals — that no one had seen before. Instead of following the conventional pathway of creating an AI model that can predict sepsis, Luminare was examining how it could improve workflow for hospitals. Better workflow, the team found, will naturally lead to improved sepsis detection and more timely treatments for patients.

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After successfully implementing their model at Cedars-Sinai Medical Center — which was able to decrease sepsis mortality by 18.7% and shorten the length of ICU stays by 22.5% — and several other hospitals, the Luminare team came to Mayo Clinic to test and strengthen their workflow system using Mayo Clinic Platform’s dataset.

“Without going through Accelerate, I don’t think our company would have gotten to where we are today,” says CEO Sarma Velamuri, M.D.

Dr. Velamuri looks forward to enhancing and expanding Luminare’s digital tool and bringing it to market in the near future, thanks to the partnership of the Accelerate team and the boost Luminare has received as one of the first participants in Mayo Clinic Platform’s Solutions Studio (which has provided additional development and validation for Luminare’s digital tool).

“Our top goal is expansion in the U.S. healthcare system, and then internationally,” Dr. Velamuri says. “We want to be the leading player in sepsis and set the benchmarks for care. We want to say, ‘Look, here’s what good sepsis care for your loved ones looks like.’ And all so we can get them back home where they belong.”